MEMPHIS, Tenn. (AP) -- Luke Maye hit a jumper with 0.3 seconds left, and top-seeded North Carolina held off Kentucky 75-73 to earn the Tar Heels' second straight trip to the Final Four and 20th all-time in Sunday's showdown of college basketball's elite in the South Regional.
The Tar Heels (31-7) will play Midwest champ Oregon on Saturday in Phoenix in the national semifinal.
North Carolina took control with a 12-0 run within the final 5 minutes. Kentucky's freshmen De'Aaron Fox and Malik Monk hit three quick 3s, the last two by Monk and his second with 7.2 seconds left tied it up at 73.
Theo Pinson brought the ball down, passed back to Maye. The sophomore from Huntersville, North Carolina, knocked it down for the win with his feet on the 3-point line.
The Wildcats had one last chance, but Derek Willis' inbound pass went out of bounds on the far end.
Kentucky (32-6) will miss out on the Final Four for the second straight year.
In the other game on Sunday, Sindarius Thornwell scored 26 points and South Carolina earned its first trip to the Final Four with a 77-70 victory over Florida on Sunday.
The seventh-seeded Gamecocks (26-10) used their trademark swarming defense and some solid free throw shooting to beat their fellow Southeastern Conference Gators (27-9) in the East Regional final at Madison Square Garden.
South Carolina will face Gonzaga, the No. 1 seed from the West Regional, in the Final Four on Saturday at Glendale, Arizona.
The game was as close as expected until the final minute. There were 14 lead changes and 10 ties. The last lead change came on two free throws by Thornwell with 2:24 left that made it 65-63. Florida managed just three field goals over the final 3:55.