One person was trapped when a cement truck went off the road and into a ditch on Thursday.
The victim was rescued and airlifted to a hospital in Boulder with serious injuries, according to the Colorado State Patrol.
The crash happened on Highway 7 at mile marker 28. That's near Lyons.
Highway 7 was closed between Lyons and Peak to Peak Highway.
The cement truck spilled a load of wet cement onto the highway, but the Colorado State Patrol said hazardous materials crews were not needed.
There's no word yet what caused the crash.