Eastbound lanes of I-70 were blocked near Central City Parkway because of an overturned semi-trailer that was hauling scrap metal.
Idaho Springs Police Chief Dave Wohlers says the truck's load shifted, causing the rollover within the construction zone.
The accident happened just before 2 p.m.
The traffic was diverted around the crash by going down the exit ramp and immediately back up the on-ramp.
Wohlers added there were no injuries in the crash.
The interstate reopened at 4:15 p.m.