Weinstein faced three new charges in a Manhattan court Monday. Those charges include a criminal sex act and two counts of predatory sexual assault.
The Manhattan District Attorney's Office announced the new charges Monday.
According to local media, Weinstein entered his plea in Manhattan Supreme Court Tuesday.
A grand jury in New York found there's enough evidence against the disgraced Hollywood producer to move forward with trial.
Weinstein was arrested, processed and charged with rape, committing a criminal sex act, sex abuse and sexual misconduct.
A source told CNN that Weinstein will be charged with first- and third-degree rape in one case and a first-degree sex act in another.
Weinstein's surrender comes just after reports he was under federal investigation.
Investigators are reportedly looking into whether the film producer lured women across state lines for unlawful sex.
In allegations published in The New Yorker, four women accused Eric Schneiderman of assault and abuse.
The Weinstein Co. filed for bankruptcy in Delaware and struck a deal to sell its assets.
Investors questioned the "viability" of the deal after hearing the company was in more debt than it disclosed.