The Colorado Department of Agriculture's state veterinarian's office has placed 69 locations under quarantine after horses and one cow tested positive for Vesicular Stomatitis.
The quarantines are in Adams, Boulder, Douglas, El Paso, Larimer and Weld counties.
The viral disease can cause blisters and sores in the mouth and on the muzzle that can be very painful and even lead to lameness, according to experts.
Most confirmed cases are in horses, but the risk to cattle is significant as well," said State Veterinarian Keith Roehr.
He said that during the past two weeks, the office has has been receiving approximately 10 reports daily of animals demonstrating clinical signs that are consistent with VS.
This story was first reported by our partners at The Denver Post.