7NEWS Photojournalist Eric Goody said he could see bullet holes in the sedan, which appeared to be an Audi.
Police had a tent set up over the entire vehicle at 6:30 a.m.
The Denver Police Department had crime scene tape around several blocks while they investigated. A police spokeswoman said police don't know how the died but the death was being investigated as a homicide.
There were approximately 20 police cars in the area, according to Goody.
MLK was closed in both directions from Ash to Birch streets until about 8:15 a.m.
Investigators could not talk about the gender or identity of the victim until the family is notified.
Police did not release any information about a possible suspect.